Chemical Investigation of Mesua nagassarium (Burm. f.) Kosterm Pages 124-128

Chemical Investigation of Mesua nagassarium (Burm. f.) Kosterm
Pages 124-128
Ridwan Islam, Iftekhar Ahmed, Al Amin Sikder, Mohammad Rashedul Haque, Abdullah Al-Mansur,Mansoor Ahmed, Munawar Rasheed and Mohammad A. Rashid

DOI: http://dx.doi.org/10.6000/1927-5129.2014.10.17

Published: 17 April 2014

Abstract: Repeated chromatographic separation and purification of pet-ether and carbon tetrachloride soluble fractions of a methanol extract of stem bark of Mesua nagassarium (Burm. f.) Kosterm yielded five compounds. Extensive spectroscopic studies, including high field NMR analyses was conducted to identify these compounds which resulted to be friedelin (1), 3β-friedelanol (2),lupeol (3), 3-oxo-betulin(4) and spinasterol (5). Although compounds 13have been reported from various plant species, but 3-oxo-betulinand spinasterol have been discovered from M. nagassarium (Burm. f.) Kosterm for the first time.

Keywords: Mesua nagassarium, Clusiaceae, 3-oxo-betulin, spinasterol.