Carotid Intima-Media Thickness in Patients with Non-Alcoholic Fatty Liver Disease

Carotid Intima-Media Thickness in Patients with Non-Alcoholic Fatty Liver Disease
– Pages 333-336

Aashfa Hassan Shaikh1, Sabeen Aatif2 and Tanweer Ahmed2

1Department of Radiology, Liaquat University of Medical & Health Sciences, Jamshoro, Pakistan; 2Department of Medicine, Karachi Medical & Dental College, Karachi, Pakistan

http://dx.doi.org/10.6000/1927-5129.2013.09.42

Abstract: Objective: To measure the thickness of Carotid Intima Media (CIMT) in patients with Non-Alcoholic Fatty Liver Disease (NAFLD) and compare it with Controls, to establish the strong association of NAFLD with increased CIMT.

Method/Setting: Fifty four patients with sonographically proven NAFLD and 50 controls were examined for CIMT. Carotid scanning was performed on Aloka 3500 Doppler Unit.

Results: The mean Intima Media Thickness in NAFLD group was 0.80±0.12 and in controls 0.58±0.15 (p= <0.0001). Carotid plaque was found in 24.07% patients in NAFLD group.

Conclusion: NAFLD as an independent risk factor for atherosclerosis and cardiovascular disease. Measurement of CIMT is a reliable, non-invasive tool for early detection of atherosclerosis in these patients.

Keywords:Non-Alcoholic Fatty Liver Disease (NAFLD), Carotid Intima Media Thickness (CIMT).