In-Vitro Antileishmanial Activity of Raphanus sativus L. var. caudatus

Authors

  • Ishrat Younus Faculty of Pharmacy, Hamdard University, Karachi, Pakistan
  • Afshan Siddiq Department of Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi, Pakistan

DOI:

https://doi.org/10.6000/1927-5129.2016.12.37

Keywords:

 Leishmaniasis, Raphanus sativus L. var. caudatus, ethanolic extract.

Abstract

Leishmaniasis is a major public health problem causing significant morbidity and mortality around the world specially Asia, Africa and Latin America. The present preliminary in-vitro study reports antileishmanial potential of Raphanus sativus L. var. caudatus. Various concentrations of ethanolic extract of plant were used. The tested extract showed noteworthy inhibition (concentration – dependant) of Leishmania promastigotes. The IC50 of extract was found to be 39 μg/ml. The results of present study could be helpful in future for antileishmanial therapy.

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Published

2016-01-05

How to Cite

Ishrat Younus, & Afshan Siddiq. (2016). In-Vitro Antileishmanial Activity of Raphanus sativus L. var. caudatus. Journal of Basic & Applied Sciences, 12, 242–244. https://doi.org/10.6000/1927-5129.2016.12.37

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Section

Pharmaceutical Sciences