Human Cutaneous Leishmaniasis in Three Districts of Sindh in Pakistan


  • Farah Sharif University of Karachi, Karachi-75270, Pakistan
  • Imtiaz Ahmad University of Karachi, Karachi-75270, Pakistan
  • Rafia Rehana Ghazi Karachi University Campus, Karachi 75270, Pakistan



 Cutaneous Leishmaniasis, Human infection, Hyderabad, Jamshoro and Dadu, Sindh.


This study was conducted to record cases of cutaneous leishmaniasis in human beings from three districts i.e., Dadu, Hyderabad and Jamshoro in Sindh, Pakistan. A total number of 102 subjects of different age and sex groups were put under investigation. Ninety four (92.157%) were found positive for cutaneous leishmaniasis. The highest leishmaniasis infection (41%) was recorded in 21-30 years’ age group. The prevalence of cutaneous leishmaniasis was higher in males, (56%) than in females, (44%). The active lesion was more frequent on face (35%), on legs (26%) and on hands (25%) than other exposed parts of the body. Forty five percent of cutaneous leishmaniasis case were recorded in Dadu, 35 percent in Hyderabad, and 20 percent in Jamshoro.


Desjeux P. Public health aspects and control. Clin Deratol 1996; 14: 417-423.

Herwaldt BL. Leshmaniasis. Lancet 1999; 354: 1191-1199.

World Health Organization (WHO). Life in the twenty century; a vision for all. WHO report, Geneva, Switzerland. 1998; Vol. 31(1): 3-24.

Bhutto AM, Soomro RF, Nonaka S, Hashiguchi Y. Detection of new Endemic areas of Cutaneous Leishmaniasis in Pakistan. a 6 years’ study. Int J Dermatol 2003; 42: 543-8.

Ali N, Afrin F. Protection of mice against visceral Leishmaniasis by immunization with Promastigote antigen incorporated in Liposomes. J Parasitol 1997; 83: 70-75.

Garcia LS. Diagnostic medical parasitology Ed. 4, ASM Press, Washington, D.C. 2001.

Durrani AZ, Durrani HZ, Kamal N, Mehmood N. Prevalence of Cutaneous Leishmaniasis in Humans and Dogs in Pakistan. Pak J Zool 2011; 43(2): 263-271.86.

Nawaz R, Khan AM, Khan SU, Rauf A. Frequency of cutaneous leishmaniasis in an Afghan refugee camp at Peshawar. Gomal J Med Sci 2010; 8(1).

Bhutto AM, Soomro RF, Kurs KK. Leishmaniasis in Sindh, Pakistan. Outbreak and review of the literature. J Pak Ass Dermat 2008; 18: 212-219.

Shoaib S, Tauheed S, Hafeez A. Cutaneous leishmaniasis: an emerging childhood infection. J Ayub Med Coll Abbottabad 2007; 19(4): 40-41.

Hayat M, Ahmad I, Afaq U, Munir S, Anees M, Hussain T, Hussain M. Prevalence and molecular diagnosis of cutaneous Leishmaniasis in local population of Dir District, Khyber Pakhtunkhwa, Pakistan. Int J Pharmaceut Sci Rev Resear 2013; 21: 359-364.

Farahmand MH, Hasti N, Naeimi AS, Farzanehnejad Z. An overview of a diagnostic and epidemiologic reappraisal of Cutaneous Leishamaniasis in Iran Braz J Infect Dis 2011; 15(1): 17-21 Elsevier Editora Ltda.

Bari AU, Rahman SB. Correlation of Histopathological and Microbiological Findings in 60 cases of Cutaneous Leishamaniasis. Ind J Dermatol Venereol Leprol 2006; 72: 28-32.

Noyes HA, Reburn H, Baily JW, Smith DA. Nested- PCR-based schizodem method for identifying Leshmania kinetoplast minicircle classes directly from clinica sample and its applications to study of the epidemiology of Leshmania tropica in Pakistan. J Cli Microbial 1998; 36: 2877-81.

Rajpar GM, Khan MA, Hafiz A. Laboratory investigation of Cutaneous Leishmaniasis in Karachi. J Med Assoc 1983; 33: 248-50.




How to Cite

Farah Sharif, Imtiaz Ahmad, & Rafia Rehana Ghazi. (2017). Human Cutaneous Leishmaniasis in Three Districts of Sindh in Pakistan. Journal of Basic & Applied Sciences, 13, 611–615.