Characterization Studies on Calcium Borate Compound Modified by ZnCO3, CaCO3 and Fructose


Calcium borate
NMR spectroscopy
Medical applications
Mono and Diesters

How to Cite

El Damrawi, G., Saad, M., & Amr M. Abdelghany. (2021). Characterization Studies on Calcium Borate Compound Modified by ZnCO3, CaCO3 and Fructose. Journal of Basic & Applied Sciences, 17, 37–43.


Calcium fructoborate solid materials of formula Ca(C6H10O6BO)2 ·3.5H2O were prepared by chemical wet technique. The neutral trigonal form of boron organic ester with fructose, under the solid form, is prepared and modified in solution in the anionic tetrahedral form; the borate compound is investigated by XRD spectroscopy. An ideal strong amorphous forming material is obtained upon modification with ZnCO3 or CaCO311B NMR solids and solution and Raman spectroscopy were developed to determine different types and the amount of borate derivative present in products. The modifier portion from calcium carbonate and fructose are consumed for boron transformation from three to four coordinated units. Raman spectra of pure B2O3 confirm the presence of the borate boroxol ring as the main structural units. But different borate units are formed upon modification by calcium carbonate and fructose. Modification by ZnCO3 had a few effects on boron transformation. The chemical shift of 11 B NMR spectra is remaining unchanged upon its addition.


Militaru C, Donoiu I, Craciun A, Scorei ID, Bulearca AM, Scorei RI. Oral resveratrol and calcium fructoborate supplementation in subjects with stable angina pectoris: effects on lipid profiles, inflammation markers, and quality of life. Nutrition 2013; 29(1): 178-183.

Packard RR, Libby P. Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clinical Chemistry 2008; 54(1): 24-38.

Fan E, Zhang L, Jiang S, Bai Y. Beneficial effects of resveratrol on atherosclerosis. Journal of medicinal food 2008; 11(4): 610-614.

Okasha A, Abdelghany AM, Wassel AR, Menazea AA. Bone bonding augmentation and synergetic attitude of gamma-irradiated modified borate bioglass. Radiation Physics and Chemistry 2020; 176: 109018.

Marone PA, Heimbach JT, Nemzer B, Hunter JM. Subchronic and genetic safety evaluation of a calcium fructoborate in rats. Food and Chemical Toxicology 2016; 95: 75-88.

Allen BC, Strong PL, Price CJ, Hubbard SA, Daston GP. Benchmark dose analysis of developmental toxicity in rats exposed to boric acid. Fundamental and Applied Toxicology 1996; 32(2): 194-204.

Rondanelli M, Faliva MA, Peroni G, Infantino V, Gasparri C, Iannello G, Tartara A. Pivotal role of boron supplementation on bone health: a narrative review. Journal of Trace Elements in Medicine and Biology 2020; 126577.

Bolt HM, Başaran N, Duydu Y. Effects of boron compounds on human reproduction. Archives of toxicology 2020; 94(3): 717-724.

Bashir NZ, Krstic M. Boric acid as an adjunct to periodontal therapy: a systematic review and meta‐analysis. International Journal of Dental Hygiene 2021.

Singh AK, Kewalramani N, Mani V, Sharma A, Kumari P, Pal RP. Effects of boric acid supplementation on bone health in crossbred calves under tropical condition. Journal of Trace Elements in Medicine and Biology 2021; 63: 126647.

Scorei RI, Rotaru P. Calcium fructoborate—potential anti-inflammatory agent. Biological Trace Element Research 2011; 143(3): 1223-1238.

Miljkovic D, Scorei RI, Cimpoiaşu VM, Scorei ID. Calcium fructoborate: plant-based dietary boron for human nutrition. Journal of Dietary Supplements 2009; 6(3): 211-226.

Huber C, Setoodeh Jahromy S, Jordan C, Schreiner M, Harasek M, Werner A, Winter F. Boric acid: a high potential candidate for thermochemical energy storage. Energies 2019; 12(6): 1086.

Zachariasen WH. The crystal structure of cubic metaboric acid. Acta Crystallographica 1963; 16(5): 380-384.

Sevim F, Demir F, Bilen M, Okur H. Kinetic analysis of thermal decomposition of boric acid from thermogravimetric data. Korean Journal of Chemical Engineering 2006; 23(5): 736-740.

ElBaz N, El-Damrawi G, Abdelghany AM. Structural Role of CeO2 in the Modified Borate Glass-Ceramics. New Journal of Glass and Ceramics 2021; 11(1): 34-43.

Abdelghany AM, Rammah YS. Transparent Alumino Lithium Borate Glass-Ceramics: Synthesis, Structure and Gamma-Ray Shielding Attitude. Journal of Inorganic and Organometallic Polymers and Materials 2021; 1-9.

Lu X, Deng L, Du J, Vienna JD. Predicting boron coordination in multicomponent borate and borosilicate glasses using analytical models and machine learning. Journal of Non-Crystalline Solids 2021; 553: 120490.

Kapoor S, George HB, Betzen A, Affatigato M, Feller S. Physical properties of barium borate glasses determined over a wide range of compositions. Journal of non-crystalline solids 2000; 270(1-3): 215-222.

Yano T, Kunimine N, Shibata S, Yamane M. Structural investigation of sodium borate glasses and melts by Raman spectroscopy. II. Conversion between BO4 and BO2O− units at high temperature. Journal of Non-Crystalline Solids 2003; 321(3): 147-156.

Al-Hadeethi Y, Sayyed MI, Rammah YS. Investigations of the physical, structural, optical and gamma-rays shielding features of B2O3–Bi2O3–ZnO–CaO glasses. Ceramics International 2019; 45(16): 20724-20732.

Konijnendijk WL, Stevels J. The structure of borate glasses studied by Raman scattering. Journal of Non-Crystalline Solids 1975; 18(3): 307-331.

Kamitsos EI, Karakassides MA, Chryssikos GD. Structure of borate glasses: Pt. 1. Physics and chemistry of glasses, 1989; 30(6): 229-234.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.