Impact of Chemotherapy Treatments on Dietary Intakes of Macro and Micronutrients among Jordanian Women with Breast Cancer


Breast Cancer, Vitamins, Minerals, Dietary intake, Chemotherapy and Jordanian.

How to Cite

Safaa A. Al-Zeidaneen, MousaA.Ahmad , & Ali D. Al-Ebuos. (2018). Impact of Chemotherapy Treatments on Dietary Intakes of Macro and Micronutrients among Jordanian Women with Breast Cancer. Journal of Pharmacy and Nutrition Sciences, 8(3), 105–111.


Background: Breast cancer (BC) is the leading cause of cancer related deaths among women worldwide. Nutritional factors may account for the large variation in BC incidence around the world. Most studies have shown no link between dietary intakes and increased risk of BC.
Objective: To evaluate the dietary intake of macro and some micronutrients among BC patients with respect to chemotherapy treatment.
Methods: A total of 168 BC patients aged 20-70 years attending BC clinics at the Jordanian Royal Medical Services, Jordan were evaluated for dietary intake. The study design permitted to include 60 newly-diagnosed BC patients who were not exposed to any type of interventions and 108 recently-diagnosed BC patients (up to three months). Recently group member were sub-divided in two sub-groups to control exposure to chemotherapy. The Chemo group (have exposed to chemotherapy) and the non-chemo group (have exposed to other types of treatments interventions). Calculations were based on the computerized nutrient analysis program (the food processor nutrition and fitness analysis software (ESHA), version 10.6/.3, Salem, USA).
Results: Energy, macronutrients and micronutrients intakes were not significantly different considering exposure to chemotherapy. However, they were less than recommended in all BC patients.
Conclusion: The possible risk of dietary undernutrition among BC patients that need a careful monitoring, evaluation and managements care plan.


Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics. CA Cancer J Clin 2009; (59): 225-249.

Jordan Breast Cancer Program, Breast Cancer in Jordan. JBCP, JordanMinistry of Health, Amman 2009.

Tarawneh M, Arkoob K, Al-Nsour M, Al-Nemry O, Al-Hajawi B. Epidemiology of breast cancer in women in Jordan: patient characteristics and survivalanalysis. EMH J 2009; 16(10): 1032-1038.

Vera-Ramirez LM, Ramirez-Tortosa C, Sanchez-Rovira P, et al. Impact of diet on breastcancer risk: A review of experimental and observational studies. Crit Rev Food Sci Nutr 2013; 53: 49-75.

Mahan LK, EScott-Stump S. Krause’s Food and Nutrition Therapy. 12th edit. Saunders/Elsevier, Philadelphia 2008.

Cefalo GH. Malnutrition Risk in Cancer Patients: Suggestions for Improvement In Nutritional Care. Unpublished Master Dissertation, Utah State University, Logan- Utah 2009.

Nelson A, Walsh D, Sheehan A. The cancer anorexia- cachexia syndrome. J Clin Onc 1994; 12: 213-225.

Elliot L. The Clinical Guide to Oncology Nutrition, (2nd ed), American Dietetic Association 2006; 72-87.

National Cancer Institute, Breast Cancer Overview: 2013.

Bjorge T, Lukanova A, Jonsson H. et al. Metabolic syndrome and breast cancer in the me-can (metabolic syndrome and cancer) project. Cancer Epidemiol Biomarkers Prev 2010; 19(7): 1737-45.

Dal Maso L, Zucchetto A, Talamini R, et al. Effect of obesity and other lifestyle factors on mortality in women with breast cancer. Int J Cancer 2008; 123: 2188-2194.

Demark-Wahnefried W, Peterson BL, Winer EP. et al. Changes in weight, body composition and factors influencing energy balance among premenopausal breast cancer patients receiving adjuvant chemotherapy. J Clin Oncol 2001; 19: 2381-2389.

Amirkalali B, Sharifi F, Fakhrzadeha H, et al. Low serum leptin serves as a biomarkerof malnutrition in elderly patients. Nutr Res 2010; 30: 314-319.

Wojtaszek CA, Kochis LM,Cunningham, RS. Nutrition impactsymptoms in the oncology patient. Oncology Issues 2002; 17(2): 15-7.

Kurniawan A. Nutritional Status and Quality of Life in Breast Cancer Patients in Karawaci General Hospital. Indonesian Journal of Cancer 2016; 10: 1-4.

Zorlini R, Akemi Abe Cairo A, Salete Costa Gurgel M. Nutritional status of patients with gynecologic and breast cancer. Nutricion Hospitalaria 2008; 23: 577-8.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright (c) 2018 Safaa A. Al-Zeidaneen , Mousa A. Ahmad  , Ali D. Al-Ebuos