A Synthesis and Review of Medicinal uses, Phytochemistry and Pharmacological Properties of Maerua crassifolia Forssk. (Capparaceae)
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Keywords

Capparaceae, ethnopharmacology, indigenous knowledge, Maerua crassifolia, traditional medicine.

How to Cite

Alfred Maroyi. (2020). A Synthesis and Review of Medicinal uses, Phytochemistry and Pharmacological Properties of Maerua crassifolia Forssk. (Capparaceae). Journal of Pharmacy and Nutrition Sciences, 10(5), 182–189. https://doi.org/10.29169/1927-5951.2020.10.05.2

Abstract

Maerua crassifolia Forssk. is an evergreen tree widely used as traditional medicine throughout its distributional range in the Sahel region, peninsular Arabia east to Pakistan, east and west Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of M. crassifolia. Documented information on medicinal uses, phytochemical and pharmacological properties of M. crassifolia was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. This study revealed that the bark, fruit, leaf and twig infusion and/or decoction of M. crassifolia are mainly used as ethnoveterinary medicine, and traditional medicine for cephalalgia, headache, fever, malaria, wounds, skin infections, toothache and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, amino acids, betaines, cardiac glycosides, fatty acids, flavonoids, lignan glucosides, phenolics, quaternary ammonium compounds, saponins, steroids, tannins and terpenoids. The M. crassifolia extracts exhibited antibacterial, anti-diarrhoeal, analgesic, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, antitrypanosomal, antipyretic and cytotoxicity activities. Maerua crassifolia should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.

https://doi.org/10.29169/1927-5951.2020.10.05.2
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References

Elfers RA, Grahama DG, Dewolf P. Capparidaceae. In Hubbard CE, Milne-Redhead E (Editors), Flora of Tropical East Africa. London: Crown Agents for Oversea Governments and Administrations; 1964, pp. 1-88.

Edwards S, et al. Flora of Ethiopia and Eritrea 2(1). Addis Ababa: The National Herbarium, Addis Ababa University; 2000.

Von Maydell HJ. Trees and shrubs of the Sahel: Their characteristics and uses. Eschborn: Margraf; 1986.

Bosch CH. Maerua crassifolia Forssk. In Schmelzer GH, Gurib-Fakim A (Editors), Plant resources of tropical Africa 11(2): Medicinal plants 2. Wageningen: Backhuys Publishers; 2013, pp. 162-163.

Wood JRI. A handbook of the Yemen Flora. Richmond: Royal Botanic Gardens, Kew; 1997.

Boulos L. Flora of Egypt 1. Cairo: Al Hadara Publishing; 1999.

Collenette S. Wildflowers of Saudi Arabia. Riyadh: National Commission for Wildlife Conservation and Development (NCWCD); 1999.

Jongbloed M, Western RA and Boer B. Annotated checklist for plants in the United Arab Emirates. Dubai: Zodiac Publishing; 2000.

Mosti S, Raffaelli M and Tardelli M. Contributions to the flora of central-southern Dhofar (Sultanate of Oman). Webbia 2012; 67: 65-91. https://doi.org/10.1080/00837792.2012.10670909

Darbyshire I, et al. The plants of Sudan and South Sudan. Richmond: Kew publishing, Royal Botanic Gardens, Kew; 2015.

Schmelzer GH, Gurib-Fakim A. Plant resources of tropical Africa 11(2): Medicinal plants 2. Wageningen: Backhuys Publishers; 2013.

Ellena R, Quave CL, Pieroni A. Comparative medical ethnobotany of the Senegalese community living in Turin (northwestern Italy) and in Adeane (southern Senegal). Evidence-Based Compl Alt Med 2012; article ID 604363. https://doi.org/10.1155/2012/604363

Burkill HM. The useful plants of west tropical Africa. Richmond: Royal Botanical Garden, Kew; 1985.

Morgan WTW. Ethnobotany of the Turkana: Use of plants by a pastoral people and their livestock in Kenya. Econ Bot 1981; 35(1): 96-130. https://doi.org/10.1007/BF02859220

Nordeide MB, Holm H, Oshaug A. Nutrient composition and protein quality of wild gathered foods from Mali. Int J Food Sci Nutr 1994; 45: 275-86. https://doi.org/10.3109/09637489409166168

Labidi D, Garitacelaya J. Atil (Maerua crassifolia), the toothbrush tree for people of the Sahara. Revue For Franç 1997; 49(3): 261-4. https://doi.org/10.4267/2042/5620

Cook JA, et al. Nutrient content of two indigenous plant foods of the Western Sahel: Balanites aegyptiaca and Maerua crassifolia. J Food Comp Analy 1998; 11: 221-30. https://doi.org/10.1006/jfca.1998.0582

Freiberger C, et al. Nutrient content of the edible leaves of seven wild plants from Niger. Pl Foods Human Nutr 1998; 57-69.

Bourlière F, Howell C. African ecology and human evolution. London: Routledge; 2004.

Pieroni A, Price LL. Eating and healing: Traditional food as medicine. Binghamton: Haworth Press; 2006. https://doi.org/10.1201/9781482293616

Lulekal E, et al. Wild edible plants in Ethiopia: A review on their potential to combat food insecurity. Afrika Focus 2011; 24(2): 71-121. https://doi.org/10.21825/af.v24i2.4998

Hamidou A, et al. Uses and preferences of woody species in two protected forests of Dan Kada Dodo and Dan Gado in Niger. J Hort For 2015; 7(6): 149-59. https://doi.org/10.5897/JHF2014.0374

Ayeni MJ, Kayode J, Uchendu OC. Ethno-medicinal survey of leafy vegetables among Igbo and Hausa tribes residents in Ado-Ekiti, Nigeria. J Bot Papers 2016; 1: 8-14.

Ouédraogo P, et al. Uses and vulnerability of ligneous species exploited by local population of northern Burkina Faso in their adaptation strategies to changing environments. Agr Food Sec 2017; 6: 15. https://doi.org/10.1186/s40066-017-0090-z

Chaib F, et al. Phytochemical investigation and biological activities of some Saharan plants from Hoggar. J Agr Sci 2015; 7(7): 163-73. https://doi.org/10.5539/jas.v7n7p163

Sajwani A, Farooq SA. Determination of the botanical and geographical origins of honey in northern Oman. Biotech Cons Species Arid Reg 2014; 1(2): 181-92.

Stiles D, Kassam A. An ethnobotanical study of Gabra plant use in Marsabit district, Kenya. J East Afr Nat History Soc Nat Museum 1991; 81: 14-37.

Kuria SG, et al. Indigenous camel mineral supplementation knowledge and practices on Manyatta based camel herds by the Rendille pastoralists of Marsabit district, Kenya. Livest Res Rural Develop 2004; 16: 7.

Calabrò S, et al. Nutritional characteristics of forages from Niger. Italian J Animal Sci 2007; 6: 271-4.

Houmey VK, et al. Forage production of a fodder tree Sahelian Maerua crassifolia Forsk. J Appl Biosci. 2012; 59: 4349-57.

Kuria SG, et al. Forage species preferred by camels (Cam-elus dromedarius) and their nutritional composition in North Eastern Kenya. Livest Res Rural Develop 2012; 24: 145.

Wasonga O, et al. Vegetation resources and their economic importance in Isiolo County, Kenya. London: IIED; 2016.

Hammiche V, Maiza K. Traditional medicine in central Sahara: Pharmacopoeia of Tassili N’ajjer. J Ethnopharmacol 2006; 105: 358-67. https://doi.org/10.1016/j.jep.2005.11.028

Volpato G, Kourková P, Zelený V. Healing war wounds and perfuming exile: the use of vegetal, animal, and mineral products for perfumes, cosmetics, and skin healing among Sahrawi refugees of Western Sahara. J Ethnobiol Ethnomed 2012; 8: 49. https://doi.org/10.1186/1746-4269-8-49

Lambert JDH, Ryden PA, Esikuri EE. Capitalizing on the bio-economic value of multi-purpose medicinal plants for the rehabilitation of drylands in sub-Saharan Africa. Washington DC: The International Bank for Reconstruction and Development; 2005.

Patzelt A, et al. The Oman botanic garden (2): Collections policy, nursery construction, expanded plant production and initial tree translocation. Sibbaldia J Bot Garden Hort 2009; 7: 83-97.

Diallo D, et al. An ethnobotanical survey of herbal drugs of Gourma district, Mali. Pharm Biol 1999; 37(1): 80-91. https://doi.org/10.1076/phbi.37.1.80.6313

Yebouk C, et al. Ethnobotanical study of medicinal plants in the Adrar province, Mauritania. J Ethnopharmacol 2020; 246: 112217. https://doi.org/10.1016/j.jep.2019.112217

Boulos L. Medicinal plants of north Africa. Michigan: Reference Publications Inc.; 1983.

Goodin JR, Northington DK. Plant resources of arid and semiarid lands: A global perspective. New York: Academic Press; 1985.

Ghazanfar SA, Al-Sabahi AMA. Medicinal plants of northern and central Oman (Arabia). Econ Bot 1993; 47(1): 89-98. https://doi.org/10.1007/BF02862209

Sakkir S, Kabshawi M, Mehairbi M. Medicinal plants diversity and their conservation status in the United Arab Emirates (UAE). J Med Plants Res 2012; 6(7): 1304-22. https://doi.org/10.5897/JMPR11.1412

Bishay DW, et al. Phytochemical study of Maerua crassifolia Forssk. growing in Egypt. Bull Pharmaceut Sci Assiut Univ 1990; 13: 39-49. https://doi.org/10.21608/bfsa.1990.70544

Abouri M, et al. An ethnobotanical survey of medicinal plants used in the Tata province, Morocco. Int J Med Plant Res 2012; 1(7): 99-123.

Idm'hand E, Msanda F, Cherif K. Ethnopharmacological review of medicinal plants used to manage diabetes in Morocco. Clinical Phytosci 2020; 6: 18. https://doi.org/10.1186/s40816-020-00166-z

El Kamali HM, El Khalifa KF. Treatment of malaria through herbal drugs in the central Sudan. Fitoterapia 1997; 68(6): 527-8.

Camacho MR, et al. Screening of plant extracts for antiprotozoal and cytotoxic activities. J Ethnopharmacol 2003; 89: 185-91. https://doi.org/10.1016/S0378-8741(03)00269-1

Ramadan MA, et al. Phytochemical study of Maerua crassifolia Forssk. growing in Egypt. Bull Pharmaceut Sci Assiut Univ 1990; 13: 39-49. https://doi.org/10.21608/bfsa.1990.70544

Irvine FR. Woody plants of Ghana, with special reference to their uses. Oxford: Oxford University Press; 1961.

Mossa JS, Al-Yahya MA, Al-Meshal IA. Medicinal plants of Saudi Arabia. Riyadh: King Saud University Press; 2000.

El-shabasy A. Survey on medicinal plants in the flora of Jizan region, Saudi Arabia. Int J Bot Stud 2016; 2(1): 38-59.

Idm'hand E, Msanda F, Cherif K. Ethnobotanical study and biodiversity of medicinal plants used in the Tarfaya province, Morocco. Acta Ecol Sinica 2020; 40: 134-44. https://doi.org/10.1016/j.chnaes.2020.01.002

Njau EA. An ethnobotanical study of medicinal plants used by the Maasai people of Many Ara-Arusha, Tanzania. MSc Dissertation. Addis Ababa: Addis Ababa University; 2001.

Mahmoud T, Gairola S. Traditional knowledge and use of medicinal plants in the Eastern Desert of Egypt: A case study from Wadi El-Gemal National Park. J Med Plants Stud 2013; 1(6): 10-17.

Khalid H, et al. Gems from traditional north-African medicine: Medicinal and aromatic plants from Sudan. Nat Prod Bioprospect 2012; 2: 92-103. https://doi.org/10.1007/s13659-012-0015-2

Doka IG, Yagi SM. Ethnobotanical survey of medicinal plants in west Kordofan (western Sudan). Ethnobot Leafl 2009; 13: 1409-16.

Antoine-Moussiaux N, Faye B,•Vias GF. Tuareg ethnoveterinary treatments of camel diseases in Agadez area (Niger). Trop Anim Health Prod 2007; 39: 83-9. https://doi.org/10.1007/s11250-007-4404-1

Volpato G, Saleh SML, Nardo AD. Ethnoveterinary of Sahrawi pastoralists of Western Sahara: camel diseases and remedies. J Ethnobiol Ethnomed 2015; 11: 54. https://doi.org/10.1186/s13002-015-0040-4

Akuodor GC, et al. Phytochemical and anti-diarrhoeal properties of methanolic leaf extract of Maerua crassifolia Forssk. European J Med Plants 2014; 4(10): 1223-31. https://doi.org/10.9734/EJMP/2014/11246

Ckilaka KC, et al. Antibacterial and antioxidant activities of methanolic leaf extract of Maerua crassifolia. J Appl Pharmaceut Sci 2015; 5(10): 147-50. https://doi.org/10.7324/JAPS.2015.501025

Akuodor GC, Analgesic, antiinflammatory and antipyretic activities of methanolic leaf extract of Maerua crassifolia. J Coastal Life Med 2016; 4(3): 225-30.

Aletan UI, Kwazo HA. Analysis of the proximate composition, anti-nutrients and mineral content of Maerua crassifolia leaves. Nigerian J Basic Appl Sci 2019; 27(1): 89-96. https://doi.org/10.4314/njbas.v27i1.12

McLean WHF, Blunden G, Jewers K. Quaternary ammonium compounds in the Capparaeae. Biochem Syst Ecol 1996; 24: 427-34. https://doi.org/10.1016/0305-1978(96)00044-0

Ibraheim ZZ. A new ionol glucoside from Maerua crassifolia Forssk. grown in Egypt. Bull Pharmaceut Sci Assiut Univ 1995; 18: 27-31. https://doi.org/10.21608/bfsa.1995.69669

Rahman MA, et al. New ionol glycosides from Maerua crassifolia Forssk grown in Egypt. Bull Pharmaceut Sci Assiut Univ 1998; 21: 89-95. https://doi.org/10.21608/bfsa.1998.67956

Rahman MA, et al. Minor constituents from Maerua crassifolia Forssk growing in Egypt. Bull Pharmaceut Sci Assiut Univ 1999; 22: 109-16. https://doi.org/10.21608/bfsa.1999.66087

Ibraheim ZZ, Ahmed AS, Ramadan MA. Lipids and triterpenes from Maerua crassifolia growing in Egypt. Saudi Pharmaceut J 2008; 16: 69-74.

Vanderjagt DJ, et al. The trypsin inhibitor content of 61 wild edible plant foods of Niger. Pl Foods Human Nutr 2000; 55: 335-46. https://doi.org/10.1023/A:1008136100545

Abdel-Sattar E, Harraz FM, El Gayed SH. Antimicrobial activity of extracts of some plants collected from the Kingdom of Saudi Arabia. J King Abdulaziz Univ Med Sci 2008; 15(1): 25-33. https://doi.org/10.4197/Med.15-1.3

Akuodor GC, et al. Antimalarial potency of the methanol leaf extract of Maerua crassifolia Forssk (Capparaceae). Asian Pacific J Trop Dis 2014; 4(1): 35-9. https://doi.org/10.1016/S2222-1808(14)60310-8

Abdel-Sattar E, Maes L, Salama MM. In vitro activities of plant extracts from Saudi Arabia against malaria, leishmaniasis, sleeping sickness and Chagas disease. Phytoth Res 2010; 24: 1322-1328. https://doi.org/10.1002/ptr.3108

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